Research at Seattle Children’s

At the forefront of pediatric medical research, Seattle Children’s is working to cure childhood disease and improve outcomes for children all over the world.

A girl in a bamboo forest

Research Saves Kids’ Lives

Seattle Children’s is a global leader driving life-changing breakthroughs for over 200 childhood diseases. But federal funding cuts are putting it all at risk.

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A History of Life-Changing Research

Since the first research lab opened in 2004, researchers at Seattle Children’s have focused on discovering and improving treatments.

Our researchers have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer and made other major contributions to pediatric medicine.

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Mapping the Developing Mind: Spatial Transcriptomics Reveals the Early Origin of Bergmann Glia

The Millen Lab solves a 50-year mystery in cerebellar development. Published in PNAS, this research uses spatial transcriptomics to redefine the timeline of Bergmann glia and correct long-standing inaccuracies in brain science.

TGF-beta Identified as Critical Driver of Ewing Sarcoma Metastasis

Findings from the Lawlor Lab reveal how Ewing sarcoma cells use TGFB2 to create a self-signaling feed-forward loop, driving them into more aggressive states and providing new insights into how a local tumor evolves to metastasize and resist treatment.

New Research Proves Timely, Targeted Care Following Teddy’s Rare Diagnosis

Teddy’s rare diagnosis receives timely treatment thanks to rapid genetic testing at Seattle Children’s.

Decoding the CAR T-Cell 'Signalosome': A New Path to Safer Cancer Therapy

Researchers at Seattle Children’s Research Institute uncover a first-of-its-kind method to predict side effects in CAR T-cell therapy, potentially paving the way for safer, more effective cancer treatments.

Learn More About Seattle Children’s Research Institute

Seattle Children’s Research Institute and Seattle Children’s Therapeutics are internationally recognized for their work in cancer therapies, genetics, neuroscience, immunology, infectious disease and bioethics.

Research Institute

Our researchers are improving pediatric healthcare by leading and participating in hundreds of research projects.

Therapeutics

Learn about our novel non-profit therapeutics development enterprise, devoted to envisioning and testing next-generation cell and gene therapies for pediatric diseases.

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Get to Know Seattle Children’s Research Institute

Learn how you can help children lead their healthiest, happiest lives by getting involved with Seattle Children's Research Institute.

Request a Speaker

Request a scientific speaker to visit your community organization or place of work to share about their life-changing research.

Attend a Research Event

Meet Our Researchers

Learn more about the researchers behind the scientific discoveries happening at Seattle Children’s Research Institute.

Explore Our Campus Virtually

Take a virtual tour of the Research Division for an insider's view of our buildings, labs and collaborative spaces.

How You Can Help

Research Saves Kids’ Lives

Seattle Children’s is a global leader driving life-changing breakthroughs for over 200 childhood diseases. But federal funding cuts are putting it all at risk.

Join or Start a Research Guild

Get together with friends, family and co-workers and turn an activity you love into a way to support research at Seattle Children's.

Find a Clinical Trial

Many children, adolescents and young adults with various conditions travel from all over the world to take part in research studies of new investigational options only available through Seattle Children’s Research Institute.

Upcoming Research Events

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